Risk and feasibility of aqueous solutions sterilization

Sep 4, 2015
This article is intended as a basic introduction on feasibility and risks of autoclaving aqueous solutions in sealed containers. Another article, Aqueous solutions in sealed containers: internal pressure under autoclaving, provides a technical approach to the matter. The feasibility and the level of risk of autoclaving sealed containers of liquid solutions under pure saturated steam conditions (e.g. in “classical” steam autoclaves, without “counterpressure”) depends on a large amount of factors. The knowledge of the mechanical resistance of the material, of which the containers are made, is very important to ascertain whether the differential pressure shall be compensated for (and to which extent), or may not be compensated for.
Author: Mascherpa, Vittorio.

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